If the “Initio Combo” thing disappears, then that’s the problem: Windows 10 is mistaking your Blu-Ray drive for this useless Initio thing. If so, see what happens if you unplug the external drive. If your external drive is completely missing from Device Manager, look to see if there is an entry called “Initio Combo Device Class”. First, look to see if the drive is listed there but with an exclamation mark next to it if so, that’s a different problem and you’ll need to look somewhere else for the solution. With the external drive plugged into the USB ports, open up the Device Manager (if you don’t know how, simply type “device manager” into the search box and click on it). I found the solution here: What follows is the info I got from there, rewritten for completely ignorant people (like me). It was as if the drive was completely invisible to Windows 10. I could hear that its power was on, but the drive did not appear in “This PC” and neither did it appear in the Device Manager. When I upgraded from Windows 8.1 to Windows 10, the external drive no longer worked.

Specifically, it is the Asus SBW-06D2x-U here: I have an external Blu-Ray/DVD external drive for my Windows laptop.